Bluetongue virus genetic and phenotypic diversity : towards identifying 1 the molecular determinants that influence virulence and transmission
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چکیده
Bluetongue virus genetic and phenotypic diversity: towards identifying 1 the molecular determinants that influence virulence and transmission 2 potential 3 4 Peter Coetzee, Moritz Van Vuuren , Maria Stokstad, Mette Myrmel, Estelle. H. Venter 5 6 Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of 7 Pretoria, Private Bag X04, Onderstepoort, Pretoria, 0110, South Africa 8 2 Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, P. 9 O. Box 8146, Oslo, Norway 10 Department of Production Animal Clinical Sciences, Norwegian School of Veterinary Science, P. 11 O. Box 8146, Department 0033, Oslo, Norway 12 13 Corresponding author 14 15 Email addresses: 16 EHV: [email protected] 17
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The evolution of bluetongue virus: genetic and phenotypic diversity of field strains.
Bluetongue virus (BTV), the aetiological agent of bluetongue (BT), is a small (about 70 nm in diameter) icosahedral virus with a genome composed of ten linear segments of double-stranded RNA (dsRNA), which is packaged within an icosahedral nucleocapsid composed of seven structural proteins. The BTV genome evolves rapidly via genetic drift, reassortment of genome segments (genetic shift) and int...
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